CpG ODN1826 as a Promising Mucin1-Maltose-Binding Protein Vaccine Adjuvant Induced DC Maturation and Enhanced Antitumor Immunity

Mucin 1 (MUC1), being an oncogene, is an attractive target in tumor immunotherapy. Maltose binding protein (MBP) is a potent built-in adjuvant to enhance protein immunogenicity. Thus, a recombinant MUC1 and MBP antitumor vaccine (M-M) was constructed in our laboratory. To enhance the antitumor immun...

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Detalles Bibliográficos
Autores principales: Jie, Jing, Zhang, Yixin, Zhou, Hongyue, Zhai, Xiaoyu, Zhang, Nannan, Yuan, Hongyan, Ni, Weihua, Tai, Guixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877781/
https://www.ncbi.nlm.nih.gov/pubmed/29558459
http://dx.doi.org/10.3390/ijms19030920

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