HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation

Interleukin-18 (IL-18) is a pleiotropic cytokine of the IL-1 family with multiple context dependent functions. We and others have shown that HIV infection is accompanied by increased circulating levels of IL-18 along with decreased levels of its antagonist, Interleukin-18 Binding Protein (IL-18BP)....

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Detalles Bibliográficos
Autores principales: Allam, Ossama, Samarani, Suzanne, Mehraj, Vikram, Jenabian, Mohammad-Ali, Tremblay, Cecile, Routy, Jean-Pierre, Amre, Devendra, Ahmad, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877838/
https://www.ncbi.nlm.nih.gov/pubmed/29601578
http://dx.doi.org/10.1371/journal.pone.0194185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877838/
https://www.ncbi.nlm.nih.gov/pubmed/29601578
http://dx.doi.org/10.1371/journal.pone.0194185

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