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Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma

Diseases of the brain involve early axon dysfunction that often precedes outright degeneration. Pruning of dendrites and their synapses represents a potential driver of axonopathy by reducing activity. Optic nerve degeneration in glaucoma, the world’s leading cause of irreversible blindness, involve...

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Detalles Bibliográficos
Autores principales: Risner, Michael L., Pasini, Silvia, Cooper, Melissa L., Lambert, Wendi S., Calkins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877940/
https://www.ncbi.nlm.nih.gov/pubmed/29463759
http://dx.doi.org/10.1073/pnas.1714888115