Diagnostic utility of telomere length testing in a hospital-based setting

Telomere length (TL) predicts the onset of cellular senescence in vitro but the diagnostic utility of TL measurement in clinical settings is not fully known. We tested the value of TL measurement by flow cytometry and FISH (flowFISH) in patients with mutations in telomerase and telomere maintenance...

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Detalles Bibliográficos
Autores principales: Alder, Jonathan K., Hanumanthu, Vidya Sagar, Strong, Margaret A., DeZern, Amy E., Stanley, Susan E., Takemoto, Clifford M., Danilova, Ludmilla, Applegate, Carolyn D., Bolton, Stephen G., Mohr, David W., Brodsky, Robert A., Casella, James F., Greider, Carol W., Jackson, J. Brooks, Armanios, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877993/
https://www.ncbi.nlm.nih.gov/pubmed/29463756
http://dx.doi.org/10.1073/pnas.1720427115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877993/
https://www.ncbi.nlm.nih.gov/pubmed/29463756
http://dx.doi.org/10.1073/pnas.1720427115

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