Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death

Gasdermin D (GSDMD) is considered a proinflammatory factor that mediates pyroptosis in macrophages to protect hosts from intracellular bacteria. Here, we reveal that GSDMD deficiency paradoxically augmented host responses to extracellular Escherichia coli, mainly by delaying neutrophil death, which...

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Detalles Bibliográficos
Autores principales: Kambara, Hiroto, Liu, Fei, Zhang, Xiaoyu, Liu, Peng, Bajrami, Besnik, Teng, Yan, Zhao, Li, Zhou, Shiyi, Yu, Hongbo, Zhou, Weidong, Silberstein, Leslie E., Cheng, Tao, Han, Mingzhe, Xu, Yuanfu, Luo, Hongbo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878047/
https://www.ncbi.nlm.nih.gov/pubmed/29539421
http://dx.doi.org/10.1016/j.celrep.2018.02.067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878047/
https://www.ncbi.nlm.nih.gov/pubmed/29539421
http://dx.doi.org/10.1016/j.celrep.2018.02.067

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