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Biosynthesis of fragin is controlled by a novel quorum sensing signal

Members of the diazeniumdiolate class of natural compounds show potential for drug development because of their antifungal, antibacterial, antiviral, and antitumor activities. Yet, their biosynthesis has remained elusive to date. Here, we identify a gene cluster directing the biosynthesis of the dia...

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Detalles Bibliográficos
Autores principales: Jenul, Christian, Sieber, Simon, Daeppen, Christophe, Mathew, Anugraha, Lardi, Martina, Pessi, Gabriella, Hoepfner, Dominic, Neuburger, Markus, Linden, Anthony, Gademann, Karl, Eberl, Leo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878181/
https://www.ncbi.nlm.nih.gov/pubmed/29602945
http://dx.doi.org/10.1038/s41467-018-03690-2

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