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Inhibiting autophagy overcomes docetaxel resistance in castration-resistant prostate cancer cells

BACKGROUND: This study investigates the docetaxel-resistant mechanism and explores the effect of tea polyphenols (TP) on autophagy and its related mechanism in human castration-resistant prostate cancer (CRPC) cell lines PC3 and DU145. METHODS: Immunofluorescence assay and annexin V-FITC/PI double s...

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Detalles Bibliográficos
Autores principales: Wang, Quan, He, Wei-Yang, Zeng, Yi-Zhou, Hossain, Arman, Gou, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878207/
https://www.ncbi.nlm.nih.gov/pubmed/29460131
http://dx.doi.org/10.1007/s11255-018-1801-5