Caffeine to prevent respiratory failure and improve outcome in infant pertussis

Pertussis remains a dangerous disease for children around the world, especially for infants less than 6 months old. In this age group, high mortality and morbidity have been linked to the effects of the pertussis toxin, including lymphocytosis, pulmonary hyperviscosity and pulmonary hypertension. Th...

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Detalles Bibliográficos
Autores principales: Evered, John, Pfeifer, Eric, Gracianette, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Novel Treatment (New Drug/Intervention; Established Drug/Procedure in New Situation)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878332/
https://www.ncbi.nlm.nih.gov/pubmed/29592985
http://dx.doi.org/10.1136/bcr-2017-223102
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author Evered, John
Pfeifer, Eric
Gracianette, Matthew
author_facet Evered, John
Pfeifer, Eric
Gracianette, Matthew
author_sort Evered, John
collection PubMed
description Pertussis remains a dangerous disease for children around the world, especially for infants less than 6 months old. In this age group, high mortality and morbidity have been linked to the effects of the pertussis toxin, including lymphocytosis, pulmonary hyperviscosity and pulmonary hypertension. This paper reports on an infant with pertussis who received therapeutic caffeine. Caffeine might improve outcomes in pertussis by preventing apnoea, improving respiratory drive and decreasing pulmonary complications.
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spelling pubmed-58783322018-04-03 Caffeine to prevent respiratory failure and improve outcome in infant pertussis Evered, John Pfeifer, Eric Gracianette, Matthew BMJ Case Rep Novel Treatment (New Drug/Intervention; Established Drug/Procedure in New Situation) Pertussis remains a dangerous disease for children around the world, especially for infants less than 6 months old. In this age group, high mortality and morbidity have been linked to the effects of the pertussis toxin, including lymphocytosis, pulmonary hyperviscosity and pulmonary hypertension. This paper reports on an infant with pertussis who received therapeutic caffeine. Caffeine might improve outcomes in pertussis by preventing apnoea, improving respiratory drive and decreasing pulmonary complications. BMJ Publishing Group 2018-03-28 /pmc/articles/PMC5878332/ /pubmed/29592985 http://dx.doi.org/10.1136/bcr-2017-223102 Text en © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Novel Treatment (New Drug/Intervention; Established Drug/Procedure in New Situation)
Evered, John
Pfeifer, Eric
Gracianette, Matthew
Caffeine to prevent respiratory failure and improve outcome in infant pertussis
title Caffeine to prevent respiratory failure and improve outcome in infant pertussis
title_full Caffeine to prevent respiratory failure and improve outcome in infant pertussis
title_fullStr Caffeine to prevent respiratory failure and improve outcome in infant pertussis
title_full_unstemmed Caffeine to prevent respiratory failure and improve outcome in infant pertussis
title_short Caffeine to prevent respiratory failure and improve outcome in infant pertussis
title_sort caffeine to prevent respiratory failure and improve outcome in infant pertussis
topic Novel Treatment (New Drug/Intervention; Established Drug/Procedure in New Situation)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878332/
https://www.ncbi.nlm.nih.gov/pubmed/29592985
http://dx.doi.org/10.1136/bcr-2017-223102
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