Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy

Autophagy is an intracellular degradation system that ensures a dynamic recycling of a variety of building blocks required for self-renewal, homeostasis, and cell survival under stress. We used primary acute myeloid leukemia (AML) samples and human AML cell lines to investigate the regulatory mechan...

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Detalles Bibliográficos
Autores principales: Jin, Jing, Britschgi, Adrian, Schläfli, Anna M., Humbert, Magali, Shan-Krauer, Deborah, Batliner, Jasmin, Federzoni, Elena A., Ernst, Marion, Torbett, Bruce E., Yousefi, Shida, Simon, Hans-Uwe, Tschan, Mario P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878891/
https://www.ncbi.nlm.nih.gov/pubmed/29743969
http://dx.doi.org/10.1155/2018/1482795

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