Selective Histone Deacetylase 6 Inhibitor 23BB Alleviated Rhabdomyolysis-Induced Acute Kidney Injury by Regulating Endoplasmic Reticulum Stress and Apoptosis

Histone deacetylase 6 (HDAC6) contributed to the pathogenesis of rhabdomyolysis-induced acute kidney injury (AKI) and selective inhibition of HDAC6 activity may be a promising strategy for the treatment of AKI. Compound 23BB as a highly selective HDAC6 inhibitor was designed, synthesized by our lab...

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Detalles Bibliográficos
Autores principales: Feng, Yuying, Huang, Rongshuang, Guo, Fan, Liang, Yan, Xiang, Jin, Lei, Song, Shi, Min, Li, Lingzhi, Liu, Jing, Feng, Yanhuan, Ma, Liang, Fu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879111/
https://www.ncbi.nlm.nih.gov/pubmed/29632491
http://dx.doi.org/10.3389/fphar.2018.00274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879111/
https://www.ncbi.nlm.nih.gov/pubmed/29632491
http://dx.doi.org/10.3389/fphar.2018.00274

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