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Adjuvant-Associated Peripheral Blood mRNA Profiles and Kinetics Induced by the Adjuvanted Recombinant Protein Candidate Tuberculosis Vaccine M72/AS01 in Bacillus Calmette–Guérin-Vaccinated Adults
Systems biology has the potential to identify gene signatures associated with vaccine immunogenicity and protective efficacy. The main objective of this study was to identify optimal postvaccination time points for evaluating peripheral blood RNA expression profiles in relation to vaccine immunogeni...
Autores principales: | van den Berg, Robert A., De Mot, Laurane, Leroux-Roels, Geert, Bechtold, Viviane, Clement, Frédéric, Coccia, Margherita, Jongert, Erik, Evans, Thomas G., Gillard, Paul, van der Most, Robbert G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879450/ https://www.ncbi.nlm.nih.gov/pubmed/29632533 http://dx.doi.org/10.3389/fimmu.2018.00564 |
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