CRISPR/Cas9-induced shank3b mutant zebrafish display autism-like behaviors

BACKGROUND: Human genetic and genomic studies have supported a strong causal role of SHANK3 deficiency in autism spectrum disorder (ASD). However, the molecular mechanism underlying SHANK3 deficiency resulting in ASD is not fully understood. Recently, the zebrafish has become an attractive organism...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chun-xue, Li, Chun-yang, Hu, Chun-chun, Wang, Yi, Lin, Jia, Jiang, Yong-hui, Li, Qiang, Xu, Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879542/
https://www.ncbi.nlm.nih.gov/pubmed/29619162
http://dx.doi.org/10.1186/s13229-018-0204-x

Ejemplares similares

Ejemplares similares