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Why was PERV not transmitted during preclinical and clinical xenotransplantation trials and after inoculation of animals?
Porcine endogenous retroviruses (PERVs) are present in the genome of all pigs, they infect certain human cells and therefore pose a special risk for xenotransplantation using pig cells, tissues and organs. Xenotransplantation is being developed in order to alleviate the reduced availability of human...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879552/ https://www.ncbi.nlm.nih.gov/pubmed/29609635 http://dx.doi.org/10.1186/s12977-018-0411-8 |