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Airway disease phenotypes in animal models of cystic fibrosis

In humans, cystic fibrosis (CF) lung disease is characterised by chronic infection, inflammation, airway remodelling, and mucus obstruction. A lack of pulmonary manifestations in CF mouse models has hindered investigations of airway disease pathogenesis, as well as the development and testing of pot...

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Detalles Bibliográficos
Autores principales: McCarron, Alexandra, Donnelley, Martin, Parsons, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879563/
https://www.ncbi.nlm.nih.gov/pubmed/29609604
http://dx.doi.org/10.1186/s12931-018-0750-y