Cargando…
Airway disease phenotypes in animal models of cystic fibrosis
In humans, cystic fibrosis (CF) lung disease is characterised by chronic infection, inflammation, airway remodelling, and mucus obstruction. A lack of pulmonary manifestations in CF mouse models has hindered investigations of airway disease pathogenesis, as well as the development and testing of pot...
Autores principales: | McCarron, Alexandra, Donnelley, Martin, Parsons, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879563/ https://www.ncbi.nlm.nih.gov/pubmed/29609604 http://dx.doi.org/10.1186/s12931-018-0750-y |
Ejemplares similares
-
To bead or not to bead: A review of Pseudomonas aeruginosa lung infection models for cystic fibrosis
por: Reyne, Nicole, et al.
Publicado: (2023) -
Essential Fatty Acid Deficiency in Cystic Fibrosis Disease Progression: Role of Genotype and Sex
por: Shrestha, Nirajan, et al.
Publicado: (2022) -
Single-Dose Lentiviral Mediated Gene Therapy Recovers CFTR Function in Cystic Fibrosis Knockout Rats
por: Reyne, Nicole, et al.
Publicado: (2021) -
Effective viral-mediated lung gene therapy: is airway surface preparation necessary?
por: McCarron, Alexandra, et al.
Publicado: (2022) -
Breaching the Delivery Barrier: Chemical and Physical Airway Epithelium Disruption Strategies for Enhancing Lentiviral-Mediated Gene Therapy
por: McCarron, Alexandra, et al.
Publicado: (2021)