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Omega-3 fatty acid DHA modulates p53, survivin, and microRNA-16-1 expression in KRAS-mutant colorectal cancer stem-like cells

BACKGROUND: The presence of chemotherapy-resistant colorectal cancer stem cells (CCSCs) with KRAS mutation is thought to be one of the primary causes for treatment failure in colorectal cancer (CRC). P53, survivin, and microRNA-16-1 are challenging targets for anticancer drugs which are associated w...

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Detalles Bibliográficos
Autores principales:	Sam, Mohammad Reza, Tavakoli-Mehr, Mohammad, Safaralizadeh, Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879572/ https://www.ncbi.nlm.nih.gov/pubmed/29619114 http://dx.doi.org/10.1186/s12263-018-0596-4

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