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SGK1 inhibition-induced autophagy impairs prostate cancer metastasis by reversing EMT
BACKGROUND: Despite SGK1 has been identified and characterized as a tumor-promoting gene, the functions and underlying mechanisms of SGK1 involved in metastasis regulation have not yet been investigated in cancer. METHODS: We investigated the cellular responses to GSK650394 treatment and SGK1 silenc...
Autores principales: | Liu, Weiwei, Wang, Xuchu, Wang, Yiyun, Dai, Yibei, Xie, Yiyi, Ping, Ying, Yin, Binbin, Yu, Pan, Liu, Zhenping, Duan, Xiuzhi, Liao, Zhaoping, Chen, Yuhua, Liu, Chunhua, Li, Xiang, Tao, Zhihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879613/ https://www.ncbi.nlm.nih.gov/pubmed/29609629 http://dx.doi.org/10.1186/s13046-018-0743-1 |
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