Immunogenicity of a Fap2 peptide mimotope of Fusobacterium nucleatum and its potential use in the diagnosis of colorectal cancer

BACKGROUND: The role of Fusobacterium nucleatum Fap2 protein in the development of colorectal cancer has recently been explained. Fap2, when bound to the human inhibitory receptor, TIGIT, inhibits the cytotoxic activity of natural killer (NK) cells against cancer cells, thus, allowing proliferation...

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Detalles Bibliográficos
Autores principales: Guevarra, Leonardo A., Afable, Andrea Claudine F., Belza, Patricia Joyce O., Dy, Karen Joy S., Lee, Scott Justin Q., Sy-Ortin, Teresa T., Albano, Pia Marie S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879760/
https://www.ncbi.nlm.nih.gov/pubmed/29619076
http://dx.doi.org/10.1186/s13027-018-0184-7

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