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IDEA intervention to prevent depressive symptoms and promote well-being in early-stage dementia: protocol for a randomised controlled feasibility study
OBJECTIVE: Depressive symptoms are common among people with dementia, impacting quality of life and cognitive and functional decline. Currently, little is known about the acceptability and feasibility of psychological interventions for people with mild dementia, with recent reviews identifying the n...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879789/ https://www.ncbi.nlm.nih.gov/pubmed/29439085 http://dx.doi.org/10.1136/bmjopen-2017-021074 |
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author | Tuijt, Remco Livingston, Gill Gould, Rebecca L Jones, Rebecca Verdaguer, Elisabet Sole Orgeta, Vasiliki |
author_facet | Tuijt, Remco Livingston, Gill Gould, Rebecca L Jones, Rebecca Verdaguer, Elisabet Sole Orgeta, Vasiliki |
author_sort | Tuijt, Remco |
collection | PubMed |
description | OBJECTIVE: Depressive symptoms are common among people with dementia, impacting quality of life and cognitive and functional decline. Currently, little is known about the acceptability and feasibility of psychological interventions for people with mild dementia, with recent reviews identifying the need for further evidence. Developing and evaluating psychological interventions to prevent and treat these symptoms is, therefore, an important clinical and research priority. This protocol describes a study testing the acceptability and feasibility of a manual-based behavioural activation (BA) intervention for preventing and treating depressive symptoms in people with mild dementia. The aim of this study is to explore the feasibility of conducting a pragmatic multicentre randomised controlled trial of clinical effectiveness of an eight-session intervention. The Intervention to prevent Depressive symptoms and promote well-being in EArly-stage dementia (IDEA) programme supports people with dementia and their family carers in identifying and scheduling enjoyable and meaningful activities. METHODS AND ANALYSIS: Sixty people who have received a diagnosis of dementia of any type in the last 6 months will be recruited via memory clinics. Further criteria are a Mini-Mental State Examination score of ≥20, and a family carer who can assist with the intervention. Consenting participants will be randomised in a ratio of 2:1 to BA or to treatment as usual. Analyses will estimate parameters such as rates of recruitment, retention and number of sessions completed. Questionnaires measuring depressive symptoms and quality of life for both the person with dementia and their carer will be completed at baseline, 3 and 6 months. Qualitative interviews will explore acceptability of the intervention, study procedures and experiences of the sessions. ETHICS AND DISSEMINATION: This study received a favourable ethical opinion from the London Camberwell St Giles Research Ethics Committee (16/LO/0540). We will disseminate findings at key conferences, the Alzheimer’s Society and University College London websites and local stakeholder events. TRIAL REGISTRATION NUMBER: ISRCTN75503960; Pre-results. |
format | Online Article Text |
id | pubmed-5879789 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-58797892018-04-03 IDEA intervention to prevent depressive symptoms and promote well-being in early-stage dementia: protocol for a randomised controlled feasibility study Tuijt, Remco Livingston, Gill Gould, Rebecca L Jones, Rebecca Verdaguer, Elisabet Sole Orgeta, Vasiliki BMJ Open Neurology OBJECTIVE: Depressive symptoms are common among people with dementia, impacting quality of life and cognitive and functional decline. Currently, little is known about the acceptability and feasibility of psychological interventions for people with mild dementia, with recent reviews identifying the need for further evidence. Developing and evaluating psychological interventions to prevent and treat these symptoms is, therefore, an important clinical and research priority. This protocol describes a study testing the acceptability and feasibility of a manual-based behavioural activation (BA) intervention for preventing and treating depressive symptoms in people with mild dementia. The aim of this study is to explore the feasibility of conducting a pragmatic multicentre randomised controlled trial of clinical effectiveness of an eight-session intervention. The Intervention to prevent Depressive symptoms and promote well-being in EArly-stage dementia (IDEA) programme supports people with dementia and their family carers in identifying and scheduling enjoyable and meaningful activities. METHODS AND ANALYSIS: Sixty people who have received a diagnosis of dementia of any type in the last 6 months will be recruited via memory clinics. Further criteria are a Mini-Mental State Examination score of ≥20, and a family carer who can assist with the intervention. Consenting participants will be randomised in a ratio of 2:1 to BA or to treatment as usual. Analyses will estimate parameters such as rates of recruitment, retention and number of sessions completed. Questionnaires measuring depressive symptoms and quality of life for both the person with dementia and their carer will be completed at baseline, 3 and 6 months. Qualitative interviews will explore acceptability of the intervention, study procedures and experiences of the sessions. ETHICS AND DISSEMINATION: This study received a favourable ethical opinion from the London Camberwell St Giles Research Ethics Committee (16/LO/0540). We will disseminate findings at key conferences, the Alzheimer’s Society and University College London websites and local stakeholder events. TRIAL REGISTRATION NUMBER: ISRCTN75503960; Pre-results. BMJ Publishing Group 2018-02-08 /pmc/articles/PMC5879789/ /pubmed/29439085 http://dx.doi.org/10.1136/bmjopen-2017-021074 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Neurology Tuijt, Remco Livingston, Gill Gould, Rebecca L Jones, Rebecca Verdaguer, Elisabet Sole Orgeta, Vasiliki IDEA intervention to prevent depressive symptoms and promote well-being in early-stage dementia: protocol for a randomised controlled feasibility study |
title | IDEA intervention to prevent depressive symptoms and promote well-being
in early-stage dementia: protocol for a randomised controlled feasibility
study |
title_full | IDEA intervention to prevent depressive symptoms and promote well-being
in early-stage dementia: protocol for a randomised controlled feasibility
study |
title_fullStr | IDEA intervention to prevent depressive symptoms and promote well-being
in early-stage dementia: protocol for a randomised controlled feasibility
study |
title_full_unstemmed | IDEA intervention to prevent depressive symptoms and promote well-being
in early-stage dementia: protocol for a randomised controlled feasibility
study |
title_short | IDEA intervention to prevent depressive symptoms and promote well-being
in early-stage dementia: protocol for a randomised controlled feasibility
study |
title_sort | idea intervention to prevent depressive symptoms and promote well-being
in early-stage dementia: protocol for a randomised controlled feasibility
study |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879789/ https://www.ncbi.nlm.nih.gov/pubmed/29439085 http://dx.doi.org/10.1136/bmjopen-2017-021074 |
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