Cargando…

Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no effective treatment. The epithelial-mesenchymal transition (EMT) is a critical stage during the development of fibrosis. To assess the effect of sulforaphane (SFN) on the EMT and fibrosis using an in vitro tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kyung, Sun Young, Kim, Dae Young, Yoon, Jin Young, Son, Eun Suk, Kim, Yu Jin, Park, Jeong Woong, Jeong, Sung Hwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879815/ https://www.ncbi.nlm.nih.gov/pubmed/29609658 http://dx.doi.org/10.1186/s40360-018-0204-7

Ejemplares similares

Comparison of Pharmacokinetics and Anti-Pulmonary Fibrosis-Related Effects of Sulforaphane and Sulforaphane N-acetylcysteine
por: Son, Eun Suk, et al.
Publicado: (2021)

Histone deacetylase 3 promotes alveolar epithelial–mesenchymal transition and fibroblast migration under hypoxic conditions
por: Jeong, Sung Hwan, et al.
Publicado: (2022)

The Phosphodiesterase 4 Inhibitor Roflumilast Protects against Cigarette Smoke Extract-Induced Mitophagy-Dependent Cell Death in Epithelial Cells
por: Kyung, Sun Young, et al.
Publicado: (2018)

Silibinin attenuates radiation-induced intestinal fibrosis and reverses epithelial-to-mesenchymal transition
por: Kim, Joong Sun, et al.
Publicado: (2017)

HOXA‑AS3 induces tumor progression through the epithelial‑mesenchymal transition pathway in epithelial ovarian cancer
por: Eoh, Kyung Jin, et al.
Publicado: (2023)

Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells
por: Park, So-Yeon, et al.
Publicado: (2015)

Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition
por: Cho, Jang-Hee, et al.
Publicado: (2016)

Asian Dust Particles Induce TGF-β(1) via Reactive Oxygen Species in Bronchial Epithelial Cells
por: Kyung, Sun Young, et al.
Publicado: (2012)

Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells
por: Kim, A-Young, et al.
Publicado: (2015)

Annual Change in Pulmonary Function and Clinical Characteristics of Combined Pulmonary Fibrosis and Emphysema and Idiopathic Pulmonary Fibrosis: Over a 3-Year Follow-up
por: Kim, Yu Jin, et al.
Publicado: (2014)

Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1
por: Cha, Byong-Ki, et al.
Publicado: (2016)

Transformation of Mouse Liver Cells by Methylcholanthrene Leads to Phenotypic Changes Associated with Epithelial-mesenchymal Transition
por: Oh, Jiyun, et al.
Publicado: (2014)

Coix lacryma-jobi var. ma-yuen Stapf sprout extract induces cell cycle arrest and apoptosis in human cervical carcinoma cells
por: Son, Eun Suk, et al.
Publicado: (2019)

Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition
por: Wang, Jun, et al.
Publicado: (2017)

Gland Attenuation, a Novel Morphological Feature of Colorectal Cancer: Evidence for an Epithelial-Mesenchymal Transition
por: Baek, Tae-Hwa, et al.
Publicado: (2018)

Elk-3 Contributes to the Progression of Liver Fibrosis by Regulating the Epithelial-Mesenchymal Transition
por: Li, Tian Zhu, et al.
Publicado: (2017)

Epithelial-mesenchymal transition in keloid tissue
por: Yang, Chae-Eun, et al.
Publicado: (2018)

The Clinicopathological Significance of Epithelial Mesenchymal Transition Associated Protein Expression in Head and Neck Squamous Cell Carcinoma
por: Kim, Kyu Ho, et al.
Publicado: (2014)

Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain
por: Lee, Young Min, et al.
Publicado: (2020)

Attenuation of early liver fibrosis by herbal compound “Diwu Yanggan” through modulating the balance between epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition
por: Shen, Xin, et al.
Publicado: (2014)

Resistance to the c-Met inhibitor KRC-108 induces the epithelial transition of gastric cancer cells
por: KIM, DONG CHUL, et al.
Publicado: (2016)

Epithelial–Mesenchymal Transition in the Pathogenesis of Idiopathic Pulmonary Fibrosis
por: Salton, Francesco, et al.
Publicado: (2019)

Epithelial to Mesenchymal Transition of Mesothelial Cells in Tuberculous Pleurisy
por: Kim, Changhwan, et al.
Publicado: (2011)

Sulforaphane Modulates Cell Migration and Expression of β-Catenin and Epithelial Mesenchymal Transition Markers in Breast Cancer Cells
por: BAGHERI, Mehdi, et al.
Publicado: (2020)

Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition
por: Liu, Yuan, et al.
Publicado: (2018)

Ginsenoside Rg3 attenuates pulmonary fibrosis by inhibiting endothelial to mesenchymal transition
por: Yun, Eunsik, et al.
Publicado: (2023)

E2F8 regulates the proliferation and invasion through epithelial-mesenchymal transition in cervical cancer
por: Kim, Lee Kyung, et al.
Publicado: (2020)

Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis
por: Kim, Ji-Won, et al.
Publicado: (2016)

Concentration- and Time-Dependent Effects of Benzalkonium Chloride in Human Lung Epithelial Cells: Necrosis, Apoptosis, or Epithelial Mesenchymal Transition
por: Kim, Sou Hyun, et al.
Publicado: (2020)

β-Peltoboykinolic Acid from Astilbe rubra Attenuates TGF-β1-Induced Epithelial-to-Mesenchymal Transitions in Lung Alveolar Epithelial Cells
por: Bang, In Jae, et al.
Publicado: (2019)

Effects of Metabolic Syndrome on Fibrosis in Chronic Viral Hepatitis
por: Yoon, Harry, et al.
Publicado: (2013)

TGF-β1 Receptor Inhibitor SB525334 Attenuates the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells via the TGF-β1 Signaling Pathway
por: Heo, Jung-Yoon, et al.
Publicado: (2021)

Involvement of epithelial–mesenchymal transition in liver fibrosis
por: Yu, Kangkang, et al.
Publicado: (2018)

Shikonin induces mitochondria-mediated apoptosis and attenuates epithelial-mesenchymal transition in cisplatin-resistant human ovarian cancer cells
por: Shilnikova, Kristina, et al.
Publicado: (2018)

Role of Ferroptosis in Regulating the Epithelial–Mesenchymal Transition in Pulmonary Fibrosis
por: Ling, Hong, et al.
Publicado: (2023)

The Effect of Statin on Epithelial-Mesenchymal Transition in Peritoneal Mesothelial Cells
por: Chang, Tae Ik, et al.
Publicado: (2014)

miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction
por: Morizane, Ryuji, et al.
Publicado: (2014)

Krüpple-like-factor 4 Attenuates Lung Fibrosis via Inhibiting Epithelial-mesenchymal Transition
por: Lin, Lianjun, et al.
Publicado: (2017)

Ell3 Enhances Differentiation of Mouse Embryonic Stem Cells by Regulating Epithelial-Mesenchymal Transition and Apoptosis
por: Ahn, Hee-Jin, et al.
Publicado: (2012)

Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation
por: Zhang, Rui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7aociup2mi3tjkohk4iv8mhcad