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Successful production of genome-edited rats by the rGONAD method

BACKGROUND: Recent progress in development of the CRISPR/Cas9 system has been shown to be an efficient gene-editing technology in various organisms. We recently developed a novel method called Genome-editing via Oviductal Nucleic Acids Delivery (GONAD) in mice; a novel in vivo genome editing system...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Tomoe, Namba, Masumi, Koyano, Takayuki, Fukushima, Masaki, Sato, Masahiro, Ohtsuka, Masato, Matsuyama, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879918/ https://www.ncbi.nlm.nih.gov/pubmed/29606116 http://dx.doi.org/10.1186/s12896-018-0430-5

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