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Simian Virus 40 Large T Antigen as a Model to Test the Efficacy of Flouroquinolones against Viral Helicases

Simian virus 40 large T-antigen (SV40 LT-Ag) is a 708 amino acid nuclear phosphoprotein. Among many functions of LT-Ag is its ability to perform as an ATPase-helicase, catalyzing the unwinding of viral genome during replication. The LT-Ag has been employed in the studies of helicase structure and fu...

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Detalles Bibliográficos
Autores principales:	Siddiqui, Sammer, Anwar, Muhammad F., Naeem, Sadaf, Abidi, Syed Hani, Zarina, Shamshad, Ali, Syed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2018
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879947/ https://www.ncbi.nlm.nih.gov/pubmed/29618903 http://dx.doi.org/10.6026/97320630014075

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