Tumor necrosis factor‐α‐mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice

Hepatocyte apoptosis has been implicated in the progression of nonalcoholic steatohepatitis. However, it is unclear whether the induction of tumor necrosis factor (TNF)‐α‐mediated hepatocyte apoptosis in the simple fatty liver triggers liver fibrosis. To address this question, high‐fat diet‐fed mice...

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Detalles Bibliográficos
Autores principales: Osawa, Yosuke, Kojika, Ekumi, Hayashi, Yukiko, Kimura, Masamichi, Nishikawa, Koji, Yoshio, Sachiyo, Doi, Hiroyoshi, Kanto, Tatsuya, Kimura, Kiminori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880193/
https://www.ncbi.nlm.nih.gov/pubmed/29619419
http://dx.doi.org/10.1002/hep4.1158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880193/
https://www.ncbi.nlm.nih.gov/pubmed/29619419
http://dx.doi.org/10.1002/hep4.1158

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