Cargando…
Tumor necrosis factor‐α‐mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice
Hepatocyte apoptosis has been implicated in the progression of nonalcoholic steatohepatitis. However, it is unclear whether the induction of tumor necrosis factor (TNF)‐α‐mediated hepatocyte apoptosis in the simple fatty liver triggers liver fibrosis. To address this question, high‐fat diet‐fed mice...
Autores principales: | Osawa, Yosuke, Kojika, Ekumi, Hayashi, Yukiko, Kimura, Masamichi, Nishikawa, Koji, Yoshio, Sachiyo, Doi, Hiroyoshi, Kanto, Tatsuya, Kimura, Kiminori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880193/ https://www.ncbi.nlm.nih.gov/pubmed/29619419 http://dx.doi.org/10.1002/hep4.1158 |
Ejemplares similares
-
Programmed cell death ligand 1 (PD-L1) blockade attenuates metastatic colon cancer growth in cAMP-response element-binding protein (CREB)-binding protein (CBP)/β-catenin inhibitor-treated livers
por: Osawa, Yosuke, et al.
Publicado: (2019) -
Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice
por: Osawa, Yosuke, et al.
Publicado: (2015) -
Inhibition of CBP/β‐catenin signaling ameliorated fibrosis in cholestatic liver disease
por: Kimura, Masamichi, et al.
Publicado: (2022) -
Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs
por: Nishikawa, Koji, et al.
Publicado: (2018) -
Immune Determinants in the Acquisition and Maintenance of Antibody to Hepatitis B Surface Antigen in Adults After First‐Time Hepatitis B Vaccination
por: Doi, Hiroyoshi, et al.
Publicado: (2019)