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Early and late changes in natural killer cells in response to ledipasvir/sofosbuvir treatment

Chronic hepatitis C virus (HCV) infection is characterized by dysregulated natural killer (NK) cell responses. NKs play a critical role in achieving sustained responses to interferon (IFN)‐α‐based therapy. Rapid sustained HCV‐RNA clearance is now achieved with direct‐acting antivirals (DAAs). Studie...

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Detalles Bibliográficos
Autores principales: Golden‐Mason, Lucy, McMahan, Rachel H., Kriss, Michael S., Kilgore, Alexandra L., Cheng, Linling, Dran, Rachael J., Wieland, Amanda, Rosen, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880201/
https://www.ncbi.nlm.nih.gov/pubmed/29619416
http://dx.doi.org/10.1002/hep4.1166