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Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo

The ketogenic diet (KD) is a high-fat, very-low-carbohydrate diet that triggers a fasting state by decreasing glucose and increasing ketone bodies, such as β-hydroxybutyrate (βHB). In experimental models and clinical trials, the KD has shown anti-tumor effects, possibly by reducing energy supplies t...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Jia, Ping-Ping, Liu, Qing-Le, Cong, Ming-Hua, Gao, Yun, Shi, Han-Ping, Yu, Wei-Nan, Miao, Ming-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880499/
https://www.ncbi.nlm.nih.gov/pubmed/29414764
http://dx.doi.org/10.1194/jlr.M082040