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Directed evolution to improve protein folding in vivo
Recently, several innovative approaches have been developed that allow one to directly screen or select for improved protein folding in the cellular context. These methods have the potential of not just leading to a better understanding of the in vivo folding process, they may also allow for improve...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880552/ https://www.ncbi.nlm.nih.gov/pubmed/29278775 http://dx.doi.org/10.1016/j.sbi.2017.12.003 |
| _version_ | 1783311177292447744 |
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| author | Sachsenhauser, Veronika Bardwell, James CA |
| author_facet | Sachsenhauser, Veronika Bardwell, James CA |
| author_sort | Sachsenhauser, Veronika |
| collection | PubMed |
| description | Recently, several innovative approaches have been developed that allow one to directly screen or select for improved protein folding in the cellular context. These methods have the potential of not just leading to a better understanding of the in vivo folding process, they may also allow for improved production of proteins of biotechnological interest. |
| format | Online Article Text |
| id | pubmed-5880552 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-58805522018-04-02 Directed evolution to improve protein folding in vivo Sachsenhauser, Veronika Bardwell, James CA Curr Opin Struct Biol Article Recently, several innovative approaches have been developed that allow one to directly screen or select for improved protein folding in the cellular context. These methods have the potential of not just leading to a better understanding of the in vivo folding process, they may also allow for improved production of proteins of biotechnological interest. 2017-12-23 2018-02 /pmc/articles/PMC5880552/ /pubmed/29278775 http://dx.doi.org/10.1016/j.sbi.2017.12.003 Text en http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Sachsenhauser, Veronika Bardwell, James CA Directed evolution to improve protein folding in vivo |
| title | Directed evolution to improve protein folding in vivo |
| title_full | Directed evolution to improve protein folding in vivo |
| title_fullStr | Directed evolution to improve protein folding in vivo |
| title_full_unstemmed | Directed evolution to improve protein folding in vivo |
| title_short | Directed evolution to improve protein folding in vivo |
| title_sort | directed evolution to improve protein folding in vivo |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880552/ https://www.ncbi.nlm.nih.gov/pubmed/29278775 http://dx.doi.org/10.1016/j.sbi.2017.12.003 |
| work_keys_str_mv | AT sachsenhauserveronika directedevolutiontoimproveproteinfoldinginvivo AT bardwelljamesca directedevolutiontoimproveproteinfoldinginvivo |