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The relative contribution of metabolic and structural abnormalities to diastolic dysfunction in obesity

BACKGROUND: Obesity causes diastolic dysfunction, and is one of the leading causes of heart failure with preserved ejection fraction. Myocardial relaxation is determined by both active metabolic processes such as impaired energetic status and steatosis, as well as intrinsic myocardial remodelling. H...

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Detalles Bibliográficos
Autores principales: Rayner, J J, Banerjee, R, Holloway, C J, Lewis, A J M, Peterzan, M A, Francis, J M, Neubauer, S, Rider, O J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880580/
https://www.ncbi.nlm.nih.gov/pubmed/28974742
http://dx.doi.org/10.1038/ijo.2017.239