Cargando…
Triglycerides cross the blood–brain barrier and induce central leptin and insulin receptor resistance
OBJECTIVE: Resistance at the brain receptors for leptin and insulin has been associated with increased feeding, obesity and cognitive impairments. The causal agent for central resistance is unknown but could be derived from the blood. Here we postulate whether hypertriglyceridemia, the major dyslipi...
Autores principales: | Banks, W A, Farr, S A, Salameh, T S, Niehoff, M L, Rhea, E M, Morley, J E, Hanson, A J, Hansen, K M, Craft, S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880581/ https://www.ncbi.nlm.nih.gov/pubmed/28990588 http://dx.doi.org/10.1038/ijo.2017.231 |
Ejemplares similares
-
Role of the Blood-Brain Barrier in Central Nervous System Insulin Resistance
por: Rhea, Elizabeth M., et al.
Publicado: (2019) -
The Blood–Brain Barrier, Oxidative Stress, and Insulin Resistance
por: Banks, William A., et al.
Publicado: (2021) -
The Effects of Viruses on Insulin Sensitivity and Blood–Brain Barrier Function
por: Raber, Jacob, et al.
Publicado: (2023) -
Endocytosis of insulin at the blood-brain barrier
por: Pemberton, Sarah, et al.
Publicado: (2022) -
The impact of acute rosiglitazone on insulin pharmacokinetics at the blood‐brain barrier
por: Galindo, Demi C., et al.
Publicado: (2020)