Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling

BACKGROUND: Solid epidemiological evidences connect obesity with incidence, stage and survival in pancreatic cancer. However, the underlying mechanistic basis linking adipocytes to pancreatic cancer progression remain largely elusive. We hypothesized that factors secreted by adipocytes could be resp...

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Detalles Bibliográficos
Autores principales: Carbone, C, Piro, G, Gaianigo, N, Ligorio, F, Santoro, R, Merz, V, Simionato, F, Zecchetto, C, Falco, G, Conti, G, Kamga, P T, Krampera, M, Di Nicolantonio, F, De Franceschi, L, Scarpa, A, Tortora, G, Melisi, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880584/
https://www.ncbi.nlm.nih.gov/pubmed/29151594
http://dx.doi.org/10.1038/ijo.2017.285

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