Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

Hypoxia is frequently encountered in tumors and results in the stabilization of hypoxia inducible factors (HIFs). These factors transcriptionally activate genes that allow cells to adapt to hypoxia. In cancers, hypoxia and HIFs have been associated with increased invasion, metastasis, and resistance...

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Detalles Bibliográficos
Autores principales: Bharti, Santosh K., Mironchik, Yelena, Wildes, Flonne, Penet, Marie-France, Goggins, Eibhlin, Krishnamachary, Balaji, Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880607/
https://www.ncbi.nlm.nih.gov/pubmed/29632647
http://dx.doi.org/10.18632/oncotarget.24569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880607/
https://www.ncbi.nlm.nih.gov/pubmed/29632647
http://dx.doi.org/10.18632/oncotarget.24569

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