Midlife insulin resistance, APOE genotype, and late-life brain amyloid accumulation

OBJECTIVE: To examine whether midlife insulin resistance is an independent risk factor for brain amyloid accumulation in vivo after 15 years, and whether this risk is modulated by APOE ε4 genotype. METHODS: This observational study examined 60 elderly volunteers without dementia (mean age at baselin...

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Detalles Bibliográficos
Autores principales: Ekblad, Laura L., Johansson, Jarkko, Helin, Semi, Viitanen, Matti, Laine, Hanna, Puukka, Pauli, Jula, Antti, Rinne, Juha O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880630/
https://www.ncbi.nlm.nih.gov/pubmed/29476033
http://dx.doi.org/10.1212/WNL.0000000000005214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880630/
https://www.ncbi.nlm.nih.gov/pubmed/29476033
http://dx.doi.org/10.1212/WNL.0000000000005214

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