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Conditional ablation of the prorenin receptor in nephron progenitor cells results in developmental programming of hypertension

Nephron induction during kidney development is driven by reciprocal interactions between progenitor cells (NPCs) of the cap mesenchyme (CM) and the ureteric bud (UB). The prorenin receptor (PRR) is a receptor for renin and prorenin, and an accessory subunit of the vacuolar proton pump V‐ATPase. Prev...

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Detalles Bibliográficos
Autores principales:	Song, Renfang, Kidd, Laura, Janssen, Adam, Yosypiv, Ihor V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880790/ https://www.ncbi.nlm.nih.gov/pubmed/29611334 http://dx.doi.org/10.14814/phy2.13644

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