Immunohistochemical localization of inhibin/activin subunits in adult Asian elephant (Elephas maximus) testes

Immunolocalization of inhibin-α and inhibin/activin βA and βB subunits in the testes of Asian elephant was determined. Testicular sections were immunostained with polyclonal antisera against inhibin subunit-α and inhibin/activin βA and βB using the avidin-biotin-peroxidase complex method. Positive i...

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Detalles Bibliográficos
Autores principales: CHAICHANATHONG, Sirinart, TAYA, Kazuyoshi, WATANABE, Gen, NAGAOKA, Kentaro, WAJJWALKU, Worawidh, SUDSUKH, Apichaya, THONGTIP, Nikorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2018
Materias:
Wildlife Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880841/
https://www.ncbi.nlm.nih.gov/pubmed/29375089
http://dx.doi.org/10.1292/jvms.17-0531
Descripción
Sumario:Immunolocalization of inhibin-α and inhibin/activin βA and βB subunits in the testes of Asian elephant was determined. Testicular sections were immunostained with polyclonal antisera against inhibin subunit-α and inhibin/activin βA and βB using the avidin-biotin-peroxidase complex method. Positive immunostaining against inhibin-α subunit was strongly present in Sertoli cells, and positive immunostaining for the inhibin/activin βA and βB subunits was observed in both Sertoli and Leydig cells. These results indicated that while Sertoli cells are the predominant source of inhibin and activin secretions in the testes of adult male Asian elephant, Leydig cells are a source of activin but not inhibin.

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