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How Diverse Are the Protein-Bound Conformations of Small-Molecule Drugs and Cofactors?
Knowledge of the bioactive conformations of small molecules or the ability to predict them with theoretical methods is of key importance to the design of bioactive compounds such as drugs, agrochemicals, and cosmetics. Using an elaborate cheminformatics pipeline, which also evaluates the support of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880911/ https://www.ncbi.nlm.nih.gov/pubmed/29637066 http://dx.doi.org/10.3389/fchem.2018.00068 |