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Macrophage Transactivation for Chemokine Production Identified as a Negative Regulator of Granulomatous Inflammation Using Agent-Based Modeling

Cellular activation in trans by interferons, cytokines, and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with inflammation is limited. This may be particu...

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Detalles Bibliográficos
Autores principales:	Moyo, Daniel, Beattie, Lynette, Andrews, Paul S., Moore, John W. J., Timmis, Jon, Sawtell, Amy, Hoehme, Stefan, Sampson, Adam T., Kaye, Paul M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880939/ https://www.ncbi.nlm.nih.gov/pubmed/29636754 http://dx.doi.org/10.3389/fimmu.2018.00637

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