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Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa
Background: The incidence of olfactory impairment increases with age; however, the detailed molecular and cellular mechanisms underlying this increase are yet to be determined. Methods: We examined the influence of aging on olfactory receptor neurons (ORNs), which are maintained by a unique stem cel...
Autores principales: | Ueha, Rumi, Shichino, Shigeyuki, Ueha, Satoshi, Kondo, Kenji, Kikuta, Shu, Nishijima, Hironobu, Matsushima, Kouji, Yamasoba, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880952/ https://www.ncbi.nlm.nih.gov/pubmed/29636678 http://dx.doi.org/10.3389/fnagi.2018.00086 |
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