The targeted anti‐oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue

Kidney proximal tubules (PTs) contain a high density of mitochondria, which are required to generate ATP to power solute transport. Mitochondrial dysfunction is implicated in the pathogenesis of numerous kidney diseases. Damaged mitochondria are thought to produce excess reactive oxygen species (ROS...

Descripción completa

Detalles Bibliográficos
Autores principales: Gottwald, Esther M., Duss, Michael, Bugarski, Milica, Haenni, Dominik, Schuh, Claus D., Landau, Ehud M., Hall, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880956/
https://www.ncbi.nlm.nih.gov/pubmed/29611340
http://dx.doi.org/10.14814/phy2.13667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880956/
https://www.ncbi.nlm.nih.gov/pubmed/29611340
http://dx.doi.org/10.14814/phy2.13667

Ejemplares similares