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The targeted anti‐oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue
Kidney proximal tubules (PTs) contain a high density of mitochondria, which are required to generate ATP to power solute transport. Mitochondrial dysfunction is implicated in the pathogenesis of numerous kidney diseases. Damaged mitochondria are thought to produce excess reactive oxygen species (ROS...
Autores principales: | Gottwald, Esther M., Duss, Michael, Bugarski, Milica, Haenni, Dominik, Schuh, Claus D., Landau, Ehud M., Hall, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880956/ https://www.ncbi.nlm.nih.gov/pubmed/29611340 http://dx.doi.org/10.14814/phy2.13667 |
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