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Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence

Pioneer transcription factors specifically target their recognition DNA sequences within nucleosomes. FoxA is the pioneer transcription factor that binds to the ALB1 gene enhancer in liver precursor cells, and is required for liver differentiation in embryos. The ALB1 enhancer DNA sequence is report...

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Detalles Bibliográficos
Autores principales: Takizawa, Yoshimasa, Tanaka, Hiroki, Machida, Shinichi, Koyama, Masako, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Wade, Paul A., Wolf, Matthias, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881032/
https://www.ncbi.nlm.nih.gov/pubmed/29563192
http://dx.doi.org/10.1098/rsob.170255