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The integrated stress response regulates BMP signalling through effects on translation

BACKGROUND: Developmental pathways must be responsive to the environment. Phosphorylation of eIF2α enables a family of stress-sensing kinases to trigger the integrated stress response (ISR), which has pro-survival and developmental consequences. Bone morphogenetic proteins (BMPs) regulate multiple d...

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Detalles Bibliográficos
Autores principales: Malzer, Elke, Dominicus, Caia S., Chambers, Joseph E., Dickens, Jennifer A., Mookerjee, Souradip, Marciniak, Stefan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881181/
https://www.ncbi.nlm.nih.gov/pubmed/29609607
http://dx.doi.org/10.1186/s12915-018-0503-x