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The integrated stress response regulates BMP signalling through effects on translation
BACKGROUND: Developmental pathways must be responsive to the environment. Phosphorylation of eIF2α enables a family of stress-sensing kinases to trigger the integrated stress response (ISR), which has pro-survival and developmental consequences. Bone morphogenetic proteins (BMPs) regulate multiple d...
Autores principales: | Malzer, Elke, Dominicus, Caia S., Chambers, Joseph E., Dickens, Jennifer A., Mookerjee, Souradip, Marciniak, Stefan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881181/ https://www.ncbi.nlm.nih.gov/pubmed/29609607 http://dx.doi.org/10.1186/s12915-018-0503-x |
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