Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model

INTRODUCTION: Peritoneal disseminated ovarian cancer is one of the most difficult cancers to treat with conventional anti-cancer drugs and the treatment options are very limited, although an intraperitoneal (ip) paclitaxel has shown some clinical benefit. Therefore, treatment of peritoneal dissemina...

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Detalles Bibliográficos
Autores principales: Iizuka, Kenzo, Jin, Cheng, Eshima, Kokoro, Hong, Mei Hua, Eshima, Kiyoshi, Fukushima, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881279/
https://www.ncbi.nlm.nih.gov/pubmed/29636601
http://dx.doi.org/10.2147/DDDT.S156635

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