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In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation
Conjugated linoleic acid (CLA) is a prime substrate for intra-gastric nitration giving rise to the formation of nitro-conjugated linoleic acid (NO(2)-CLA). Herein, NO(2)-CLA generation is demonstrated within the context of acute inflammatory responses both in vitro and in vivo. Macrophage activation...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881417/ https://www.ncbi.nlm.nih.gov/pubmed/29413964 http://dx.doi.org/10.1016/j.redox.2018.01.005 |