Structural mechanisms of CFTR function and dysfunction

Cystic fibrosis (CF) transmembrane conductance regulator (CFTR) chloride channel plays a critical role in regulating transepithelial movement of water and electrolyte in exocrine tissues. Malfunction of the channel because of mutations of the cftr gene results in CF, the most prevalent lethal geneti...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Tzyh-Chang, Yeh, Jiunn-Tyng, Zhang, Jingyao, Yu, Ying-Chun, Yeh, Han-I, Destefano, Samantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881446/
https://www.ncbi.nlm.nih.gov/pubmed/29581173
http://dx.doi.org/10.1085/jgp.201711946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881446/
https://www.ncbi.nlm.nih.gov/pubmed/29581173
http://dx.doi.org/10.1085/jgp.201711946

Ejemplares similares