Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

Germinal centers (GCs) are the sites where B cells undergo affinity maturation. The regulation of cellular output from the GC is not well understood. Here, we show that from the earliest stages of the GC response, plasmablasts emerge at the GC–T zone interface (GTI). We define two main factors that...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Tech, Laura, George, Laura A., Acs, Andreas, Durrett, Russell E., Hess, Henry, Walker, Lucy S.K., Tarlinton, David M., Fletcher, Anne L., Hauser, Anja Erika, Toellner, Kai-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881458/
https://www.ncbi.nlm.nih.gov/pubmed/29549115
http://dx.doi.org/10.1084/jem.20160832

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