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Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation
The adapter molecule linker for activation of T cells (LAT) orchestrates the formation of signalosomes upon T cell receptor (TCR) stimulation. LAT is present in different intracellular pools and is dynamically recruited to the immune synapse upon stimulation. However, the intracellular traffic of LA...
Autores principales: | Carpier, Jean-Marie, Zucchetti, Andres E., Bataille, Laurence, Dogniaux, Stéphanie, Shafaq-Zadah, Massiullah, Bardin, Sabine, Lucchino, Marco, Maurin, Mathieu, Joannas, Leonel D., Magalhaes, Joao Gamelas, Johannes, Ludger, Galli, Thierry, Goud, Bruno, Hivroz, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881459/ https://www.ncbi.nlm.nih.gov/pubmed/29440364 http://dx.doi.org/10.1084/jem.20162042 |
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