Signaling function of PRC2 is essential for TCR-driven T cell responses

Differentiation and activation of T cells require the activity of numerous histone lysine methyltransferases (HMT) that control the transcriptional T cell output. One of the most potent regulators of T cell differentiation is the HMT Ezh2. Ezh2 is a key enzymatic component of polycomb repressive com...

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Detalles Bibliográficos
Autores principales: Dobenecker, Marc-Werner, Park, Joon Seok, Marcello, Jonas, McCabe, Michael T., Gregory, Richard, Knight, Steven D., Rioja, Inmaculada, Bassil, Anna K., Prinjha, Rabinder K., Tarakhovsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881460/
https://www.ncbi.nlm.nih.gov/pubmed/29523590
http://dx.doi.org/10.1084/jem.20170084

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