Cargando…

STAT-3–independent production of IL-17 by mouse innate-like αβ T cells controls ocular infection

Appropriate regulation of IL-17 production in the host can mean the difference between effective control of pathogens and uncontrolled inflammation that causes tissue damage. Investigation of conventional CD4(+) T cells (Th17 cells) has yielded invaluable insights into IL-17 function and its regulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	St. Leger, Anthony J., Hansen, Anna M., Karauzum, Hatice, Horai, Reiko, Yu, Cheng-Rong, Laurence, Arian, Mayer-Barber, Katrin D., Silver, Phyllis, Villasmil, Rafael, Egwuagu, Charles, Datta, Sandip K., Caspi, Rachel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881461/ https://www.ncbi.nlm.nih.gov/pubmed/29490936 http://dx.doi.org/10.1084/jem.20170369

Ejemplares similares

Draft Reference Genome Sequence of Corynebacterium mastitidis RC, an Ocular Commensal, Isolated from Mouse Conjunctiva
por: Nagarajan, Vijayaraj, et al.
Publicado: (2022)

Microbiota as Drivers and as Therapeutic Targets in Ocular and Tissue Specific Autoimmunity
por: Salvador, Ryan, et al.
Publicado: (2021)

Mucosal immunology of the ocular surface
por: de Paiva, Cintia S., et al.
Publicado: (2022)

Human Innate Mycobacterium tuberculosis–Reactive αβTCR(+) Thymocytes
por: Gold, Marielle C, et al.
Publicado: (2008)

Microbiome and Autoimmune Uveitis
por: Horai, Reiko, et al.
Publicado: (2019)

Rapid αβ T cell responses orchestrate innate immunity in response to Staphylococcal enterotoxin A
por: Kumar, Sanjeev, et al.
Publicado: (2013)

A Molecular Docking Study Reveals That Short Peptides Induce Conformational Changes in the Structure of Human Tubulin Isotypes αβI, αβII, αβIII and αβIV
por: Ebenezer, Oluwakemi, et al.
Publicado: (2023)

Therapeutic targeting of STAT pathways in CNS autoimmune diseases
por: Egwuagu, Charles E., et al.
Publicado: (2013)

Genesis of the αβ T-cell receptor
por: Dupic, Thomas, et al.
Publicado: (2019)

Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8(+) T Cells
por: Sun, Lin, et al.
Publicado: (2016)

Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus
por: Cowan, Jennifer E., et al.
Publicado: (2014)

Use of Optical Coherence Tomography and Electroretinography to Evaluate Retinal Pathology in a Mouse Model of Autoimmune Uveitis
por: Chen, Jun, et al.
Publicado: (2013)

The transcriptional landscape of αβ T cell differentiation
por: Mingueneau, Michael, et al.
Publicado: (2013)

Centroid-Based Clustering with αβ-Divergences
por: Sarmiento, Auxiliadora, et al.
Publicado: (2019)

Innate T-αβ lymphocytes as new immunological components of anti-tumoral “off-target” effects of the tyrosine kinase inhibitor dasatinib
por: Barbarin, Alice, et al.
Publicado: (2020)

NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ–IL-27 axis
por: Chong, Wai Po, et al.
Publicado: (2015)

Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations
por: Kumbhar, Bajarang Vasant, et al.
Publicado: (2016)

Comparative Analysis of Induced vs. Spontaneous Models of Autoimmune Uveitis Targeting the Interphotoreceptor Retinoid Binding Protein
por: Chen, Jun, et al.
Publicado: (2013)

Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development
por: Lucas, Beth, et al.
Publicado: (2017)

αβ T cell receptors as predictors of health and disease
por: Attaf, Meriem, et al.
Publicado: (2015)

The contribution of αβ-tubulin curvature to microtubule dynamics
por: Brouhard, Gary J., et al.
Publicado: (2014)

The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
por: Chong, Wai Po, et al.
Publicado: (2020)

Whodunit? The Contribution of Interleukin (IL)-17/IL-22-Producing γδ T Cells, αβ T Cells, and Innate Lymphoid Cells to the Pathogenesis of Spondyloarthritis
por: Reinhardt, Annika, et al.
Publicado: (2018)

Ocular Surface as Barrier of Innate Immunity
por: Bolaños-Jiménez, Rodrigo, et al.
Publicado: (2015)

Ocular immune privilege
por: Zhou, Ru, et al.
Publicado: (2010)

Pathogenic potential of interferon αβ in acute influenza infection
por: Davidson, Sophia, et al.
Publicado: (2014)

PA28αβ: The Enigmatic Magic Ring of the Proteasome?
por: Cascio, Paolo
Publicado: (2014)

Human αβ and γδ T Cells in Skin Immunity and Disease
por: Cruz, Michelle S., et al.
Publicado: (2018)

The thymus medulla and its control of αβT cell development
por: Cosway, Emilie J., et al.
Publicado: (2020)

Structural and Biophysical Insights into the TCRαβ Complex in Chickens
por: Zhang, Lijie, et al.
Publicado: (2020)

Cryo-EM of mammalian PA28αβ-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28αβ
por: Chen, Jinhuan, et al.
Publicado: (2021)

Orchestrating an immune response against cancer with engineered immune cells expressing αβTCRs, CARs, and innate immune receptors: an immunological and regulatory challenge
por: de Witte, Moniek A., et al.
Publicado: (2015)

Too Much of a Good Thing: Extended Duration of Gut Microbiota Depletion Reverses Protection From Experimental Autoimmune Uveitis
por: Salvador, Ryan, et al.
Publicado: (2023)

Photoreceptor Cells Constitutively Express IL-35 and Promote Ocular Immune Privilege
por: Yu, Cheng-Rong, et al.
Publicado: (2022)

Retinoid Regulation of Ocular Surface Innate Inflammation
por: Alam, Jehan, et al.
Publicado: (2021)

IL-27-containing exosomes secreted by innate B-1a cells suppress and ameliorate uveitis
por: Kang, Minkyung, et al.
Publicado: (2023)

Expression of The αβ T-Cell Receptor Is Necessary for The Generation of The Thymic Medulla
por: Palmer, Donald B., et al.
Publicado: (1993)

Presenilins regulate αβ T cell development by modulating TCR signaling
por: Laky, Karen, et al.
Publicado: (2007)

Identification and characterization of polyclonal αβ T cells with dendritic cell properties
por: Kuka, Mirela, et al.
Publicado: (2012)

The molecular bases of δ/αβ T cell–mediated antigen recognition
por: Pellicci, Daniel G., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6topgi6edk393b7gbvmr39n35f