ApoE facilitates the microglial response to amyloid plaque pathology

One of the hallmarks of Alzheimer’s disease is the presence of extracellular diffuse and fibrillar plaques predominantly consisting of the amyloid-β (Aβ) peptide. Apolipoprotein E (ApoE) influences the deposition of amyloid pathology through affecting the clearance and aggregation of monomeric Aβ in...

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Detalles Bibliográficos
Autores principales: Ulrich, Jason D., Ulland, Tyler K., Mahan, Thomas E., Nyström, Sofie, Nilsson, K. Peter, Song, Wilbur M., Zhou, Yingyue, Reinartz, Mariska, Choi, Seulah, Jiang, Hong, Stewart, Floy R., Anderson, Elise, Wang, Yaming, Colonna, Marco, Holtzman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881464/
https://www.ncbi.nlm.nih.gov/pubmed/29483128
http://dx.doi.org/10.1084/jem.20171265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881464/
https://www.ncbi.nlm.nih.gov/pubmed/29483128
http://dx.doi.org/10.1084/jem.20171265

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